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A Convenient and Efficient Palladium‐Catalyzed Carbonylative Sonogashira Transformation with Formic Acid as the CO Source
Author(s) -
Peng JinBao,
Wu FuPeng,
Li ChongLiang,
Qi Xinxin,
Wu XiaoFeng
Publication year - 2017
Publication title -
european journal of organic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.825
H-Index - 155
eISSN - 1099-0690
pISSN - 1434-193X
DOI - 10.1002/ejoc.201700076
Subject(s) - chemistry , formic acid , sonogashira coupling , palladium , catalysis , carbonylation , aryl , combinatorial chemistry , activator (genetics) , organic chemistry , carbon monoxide , biochemistry , alkyl , gene
A practical, convenient, and efficient palladium‐catalyzed carbonylative Sonogashira reaction of aryl iodides was developed. With formic acid as the CO source and dicyclohexylcarbodiimide as the activator, various alkynones were produced in good to excellent yields.