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The First Plant 5,6‐Secosteroid from the Australian Arid Zone Species Frankenia foliosa
Author(s) -
Tan Yuen P.,
Savchenko Andrei I.,
Broit Natasa,
Boyle Glen M.,
Parsons Peter G.,
Williams Craig M.
Publication year - 2017
Publication title -
european journal of organic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.825
H-Index - 155
eISSN - 1099-0690
pISSN - 1434-193X
DOI - 10.1002/ejoc.201700035
Subject(s) - chemistry , botany , biology
The first B‐ring 5,6‐secosteroid isolated from plants was obtained from Frankenia foliosa , growing in Australia's arid zone. This rare secosteroid was shown to be active against all cell lines including head and neck squamous cell carcinoma (SCC) cancer cell lines that contain the Cdc25A phosphatase protein.