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Electrophilic Trifluoromethyl‐ and Fluoroalkylselenolation of Organometallic Reagents
Author(s) -
Glenadel Quentin,
Ismalaj Ermal,
Billard Thierry
Publication year - 2017
Publication title -
european journal of organic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.825
H-Index - 155
eISSN - 1099-0690
pISSN - 1434-193X
DOI - 10.1002/ejoc.201601526
Subject(s) - chemistry , reagent , electrophile , trifluoromethyl , group 2 organometallic chemistry , organometallic chemistry , combinatorial chemistry , molecule , organic chemistry , organic molecules , group (periodic table) , trifluoromethylation , main group element , computational chemistry , catalysis , transition metal , alkyl
Fluoroalkylseleno groups are emerging groups that still suffer from a lack of efficient methods for introduction onto organic molecules. Herein, we describe an efficient method to perform reactions between in situ formed fluoroalkaneselenyl chlorides and organometallic reagents. With this strategy, various fluoroalkylselenolated molecules were easily obtained. Furthermore, the Hansch parameter of the CF 3 Se group was determined for the first time.
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