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Synthesis of CF 2 H‐Substituted Pyrazolines by [3+2] Cycloaddition between CF 2 HCHN 2 and Electron‐Deficient Alkenes
Author(s) -
Li Jue,
Yu XinLing,
Cossy Janine,
Lv SongYang,
Zhang HaiLong,
Su Fu,
Mykhailiuk Pavel K.,
Wu Yong
Publication year - 2017
Publication title -
european journal of organic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.825
H-Index - 155
eISSN - 1099-0690
pISSN - 1434-193X
DOI - 10.1002/ejoc.201601462
Subject(s) - cycloaddition , chemistry , medicinal chemistry , pyrazoline , pyrazole , alkene , stereochemistry , organic chemistry , catalysis
CF 2 H‐substituted pyrazolines were synthesized by [3+2] cycloaddition between in situ generated CF 2 HCHN 2 and electron‐deficient alkenes. The representative CF 2 H‐substituted pyrazoline was easily oxidized into the CF 2 H‐substituted pyrazole, which are important in agrochemistry.

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