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Facile Synthesis of Polysubstituted Imidazoles through CBr 4 ‐Mediated Tandem Cyclization of Amidines with 1,3‐Dicarbonyl Compounds or Ketones
Author(s) -
Zhou Xiaoqiang,
Ma Haojie,
Shi Chong,
Zhang Yixin,
Liu XingXing,
Huang Guosheng
Publication year - 2017
Publication title -
european journal of organic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.825
H-Index - 155
eISSN - 1099-0690
pISSN - 1434-193X
DOI - 10.1002/ejoc.201601428
Subject(s) - chemistry , amidine , tandem , combinatorial chemistry , reaction conditions , organic chemistry , catalysis , materials science , composite material
Polysubstituted imidazoles were synthesized in a facile metal‐free CBr 4 ‐mediated tandem cyclization of amidine with 1,3‐dicarbonyl compounds or ketones. The desired products were obtained in moderate to good yields by using simple operation techniques and mild conditions.