Regioselective Arylative Ring‐Closing Reaction of 2‐Alkynylphenyl Derivatives: Formation of Arylated Benzoxazin‐2‐ones, Benzoxazin‐2‐amines and 2,3‐Disubstituted Indoles | Zendy

Minami Hideki | Zendy; Kanayama Takuya | Zendy; Tanaka Reishi | Zendy; Okamoto Noriko | Zendy; Sueda Takuya | Zendy; Yanada Reiko | Zendy

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Regioselective Arylative Ring‐Closing Reaction of 2‐Alkynylphenyl Derivatives: Formation of Arylated Benzoxazin‐2‐ones, Benzoxazin‐2‐amines and 2,3‐Disubstituted Indoles

Author(s) -

Minami Hideki,

Kanayama Takuya,

Tanaka Reishi,

Okamoto Noriko,

Sueda Takuya,

Yanada Reiko

Publication year - 2016

Publication title -

european journal of organic chemistry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.825

H-Index - 155

eISSN - 1099-0690

pISSN - 1434-193X

DOI - 10.1002/ejoc.201601162

Subject(s) - chemistry , regioselectivity , ring (chemistry) , closing (real estate) , palladium , ring closing metathesis , medicinal chemistry , organic chemistry , stereochemistry , catalysis , polymer , metathesis , political science , law , polymerization

Copper‐catalysed arylative ring‐closing reactions of 2‐alkynylphenylcarbamates and 2‐alkynylphenylureas with diaryliodonium salts gave C , N ‐double‐arylated benzoxazin‐2‐ones and C ‐arylated benzoxazin‐2‐amines, respectively, both bearing fully substituted exocyclic olefins. On the other hand, the palladium‐catalysed arylative ring‐closing reaction of 2‐alkynylphenylcarbamates gave C ‐arylated 2,3‐disubstituted indoles.

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