Synthesis of Thiazolidine‐2‐thiones through a One‐Pot A 3 ‐Coupling–Carbon Disulfide Incorporation Process | Zendy

Nechaev Anton A. | Zendy; Peshkov Anatoly A. | Zendy; Van Hecke Kristof | Zendy; Peshkov Vsevolod A. | Zendy; Van der Eycken Erik V. | Zendy

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Synthesis of Thiazolidine‐2‐thiones through a One‐Pot A 3 ‐Coupling–Carbon Disulfide Incorporation Process

Author(s) -

Nechaev Anton A.,

Peshkov Anatoly A.,

Van Hecke Kristof,

Peshkov Vsevolod A.,

Van der Eycken Erik V.

Publication year - 2017

Publication title -

european journal of organic chemistry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.825

H-Index - 155

eISSN - 1099-0690

pISSN - 1434-193X

DOI - 10.1002/ejoc.201601103

Subject(s) - chemistry , carbon disulfide , thiazolidine , aldehyde , amine gas treating , alkyne , coupling (piping) , disulfide bond , carbon fibers , combinatorial chemistry , organic chemistry , catalysis , mechanical engineering , biochemistry , materials science , composite number , engineering , composite material

A copper‐catalyzed two‐step one‐pot procedure for the synthesis of thiazolidine‐2‐thiones has been developed. The process involves a three‐component coupling of an alkyne, an aldehyde, and an amine (A 3 ‐coupling) followed by trapping the resulting propargylamine with carbon disulfide and subsequent cyclization.

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