Efficient Synthesis of Functionalized β‐Keto Esters and β‐Diketones through Regioselective Hydration of Alkynyl Esters and Alkynyl Ketones by Use of a Cationic NHC–Au I  Catalyst | Zendy

Tarigopula Chandrahas | Zendy; Thota Ganesh Kumar | Zendy; Balamurugan Rengarajan | Zendy

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Efficient Synthesis of Functionalized β‐Keto Esters and β‐Diketones through Regioselective Hydration of Alkynyl Esters and Alkynyl Ketones by Use of a Cationic NHC–Au I Catalyst

Author(s) -

Tarigopula Chandrahas,

Thota Ganesh Kumar,

Balamurugan Rengarajan

Publication year - 2016

Publication title -

european journal of organic chemistry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.825

H-Index - 155

eISSN - 1099-0690

pISSN - 1434-193X

DOI - 10.1002/ejoc.201601025

Subject(s) - chemistry , regioselectivity , cationic polymerization , acetone , catalysis , aldol condensation , solvent , organic chemistry , ketone , medicinal chemistry , condensation , polymer chemistry , physics , thermodynamics

Regioselective hydration of α‐alkynyl esters and ketones by using a cationic NHC–Au I catalyst results in β‐keto esters and β‐diketones, respectively. Controlled release of water in acetone by aldol self‐condensation under the reaction conditions makes acetone as better solvent than 1,4‐dioxane/water for the hydration of α‐alkynyl esters having sensitive ester moieties.

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