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B(C 6 F 5 ) 3 ‐Catalyzed Reduction of Aromatic and Aliphatic Nitro Groups with Hydrosilanes
Author(s) -
Porwal Digvijay,
Oestreich Martin
Publication year - 2016
Publication title -
european journal of organic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.825
H-Index - 155
eISSN - 1099-0690
pISSN - 1434-193X
DOI - 10.1002/ejoc.201600556
Subject(s) - deoxygenation , chemistry , nitro , catalysis , transition metal , medicinal chemistry , nitro compound , organic chemistry , stereochemistry , alkyl
A transition‐metal‐free method for the hydrosilane reduction of aromatic and aliphatic nitro compounds to the corresponding amines is reported. Et 3 SiH is found to be the optimal reductant in this B(C 6 F 5 ) 3 ‐catalyzed deoxygenation. The functional‐group tolerance is, however, moderate.