Cyclative Cascades of Allenamides Derived from Amino Acids: Synthesis of Annulated Indoxyl Derivatives | Zendy

Petkovic Milos | Zendy; Nasufovic Veselin | Zendy; Djukanovic Dimitrije | Zendy; Vujosevic Zorana Tokic | Zendy; Jadranin Milka | Zendy; Matovic Radomir | Zendy; Savic Vladimir | Zendy

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Cyclative Cascades of Allenamides Derived from Amino Acids: Synthesis of Annulated Indoxyl Derivatives

Author(s) -

Petkovic Milos,

Nasufovic Veselin,

Djukanovic Dimitrije,

Vujosevic Zorana Tokic,

Jadranin Milka,

Matovic Radomir,

Savic Vladimir

Publication year - 2016

Publication title -

european journal of organic chemistry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.825

H-Index - 155

eISSN - 1099-0690

pISSN - 1434-193X

DOI - 10.1002/ejoc.201600067

Subject(s) - chemistry , cascade , combinatorial chemistry , amino acid , structural motif , cascade reaction , stereochemistry , catalysis , organic chemistry , biochemistry , chromatography

Allenamides derived from amino acids participate in the cascade transformations catalyzed by Pd 0 allowing consecutive formation of two five‐membered rings. The developed methodology provides an access to annulated indoles which can be transformed to functionalized indoxyl derivatives, retaining a structural motif embedded in several natural products.

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