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Direct Synthesis of Enolizable N ‐Sulfonyl Ketimines Under Microwave Irradiation
Author(s) -
Collados Juan F.,
Harutyunyan Syuzanna R.
Publication year - 2016
Publication title -
european journal of organic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.825
H-Index - 155
eISSN - 1099-0690
pISSN - 1434-193X
DOI - 10.1002/ejoc.201600022
Subject(s) - sulfonyl , chemistry , sulfonamide , microwave irradiation , aldimine , aldehyde , microwave , combinatorial chemistry , organic chemistry , condensation , catalysis , alkyl , physics , quantum mechanics , thermodynamics
N ‐sulfonyl imines are widely used as substrates for a range of transformations. Access to N ‐sulfonyl aldimines is straightforward through direct condensation between the parent aldehyde and the sulfonamide. However, this approach is not efficient for the synthesis of enolizable N ‐sulfonyl ketimines. Herein we report a rapid and facile methodology for obtaining these products using microwave irradiation.
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