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Synthesis of Fluorine‐Containing Exoalkylidene β‐Lactams
Author(s) -
Nasr El Dine Assaad,
Grée Danielle,
Roisnel Thierry,
Caytan Elsa,
Hachem Ali,
Grée René
Publication year - 2016
Publication title -
european journal of organic chemistry
Language(s) - Uncategorized
Resource type - Journals
SCImago Journal Rank - 0.825
H-Index - 155
eISSN - 1099-0690
pISSN - 1434-193X
DOI - 10.1002/ejoc.201501347
Subject(s) - difluoride , fluorine , chemistry , combinatorial chemistry , stereochemistry , organic chemistry
The Kinugasa reaction, applied to propargylic gem ‐difluorides, allows a very direct and efficient synthesis of new exoalkylidene β‐lactams with a fluorine in the vinylic position.