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Synthesis of 5‐Substituted 1,2,3‐Triazolyl‐4‐phosphonate through Cross‐Coupling Reactions of 5‐Iodo‐1,2,3‐triazolyl‐4‐phosphonate
Author(s) -
Thiery Emilie,
You Vanny,
Mora AnneSophie,
Abarbri Mohamed
Publication year - 2016
Publication title -
european journal of organic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.825
H-Index - 155
eISSN - 1099-0690
pISSN - 1434-193X
DOI - 10.1002/ejoc.201501266
Subject(s) - phosphonate , stille reaction , aryl , chemistry , combinatorial chemistry , coupling reaction , suzuki reaction , organic chemistry , stereochemistry , catalysis , alkyl
Two methods for the preparation of 5‐iodo‐1,2,3‐triazolyl‐4‐phosphonate were explored. This compound was then functionalized by Suzuki and Stille cross‐coupling reaction to obtain 5‐aryl‐, 5‐heteroaryl‐ or 5‐alkenyl‐1,2,3‐triazolyl‐4‐phosphonates.