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Hypervalent Iodine Promoted Regioselective Oxidative C–H Functionalization: Synthesis of N ‐(Pyridin‐2‐yl)benzo[ d ]thiazol‐2‐amines
Author(s) -
Mariappan Arumugam,
Rajaguru Kandasamy,
Santharam Roja Somi,
Muthusubramanian Shanmugam,
Bhuvanesh Nattamai
Publication year - 2016
Publication title -
european journal of organic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.825
H-Index - 155
eISSN - 1099-0690
pISSN - 1434-193X
DOI - 10.1002/ejoc.201501202
Subject(s) - chemistry , hypervalent molecule , regioselectivity , oxidative phosphorylation , iodine , stereochemistry , combinatorial chemistry , medicinal chemistry , organic chemistry , catalysis , biochemistry
Biologically potent N ‐(pyridin‐2‐yl)benzo[ d ]thiazol‐2‐amines were conveniently synthesized from simple heteroaryl‐thioureas through an oxidative C–S bond formation strategy that employed phenyliodine(III) bis(trifluoroacetate) as the oxidant. This protocol features a metal‐free approach, a broad scope of substrates, short reaction times, and a simple product purification procedure.