Hypervalent Iodine Promoted Regioselective Oxidative C–H Functionalization: Synthesis of  N ‐(Pyridin‐2‐yl)benzo[ d ]thiazol‐2‐amines | Zendy

Mariappan Arumugam | Zendy; Rajaguru Kandasamy | Zendy; Santharam Roja Somi | Zendy; Muthusubramanian Shanmugam | Zendy; Bhuvanesh Nattamai | Zendy

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Hypervalent Iodine Promoted Regioselective Oxidative C–H Functionalization: Synthesis of N ‐(Pyridin‐2‐yl)benzo[ d ]thiazol‐2‐amines

Author(s) -

Mariappan Arumugam,

Rajaguru Kandasamy,

Santharam Roja Somi,

Muthusubramanian Shanmugam,

Bhuvanesh Nattamai

Publication year - 2016

Publication title -

european journal of organic chemistry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.825

H-Index - 155

eISSN - 1099-0690

pISSN - 1434-193X

DOI - 10.1002/ejoc.201501202

Subject(s) - chemistry , hypervalent molecule , regioselectivity , oxidative phosphorylation , iodine , stereochemistry , combinatorial chemistry , medicinal chemistry , organic chemistry , catalysis , biochemistry

Biologically potent N ‐(pyridin‐2‐yl)benzo[ d ]thiazol‐2‐amines were conveniently synthesized from simple heteroaryl‐thioureas through an oxidative C–S bond formation strategy that employed phenyliodine(III) bis(trifluoroacetate) as the oxidant. This protocol features a metal‐free approach, a broad scope of substrates, short reaction times, and a simple product purification procedure.

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