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Regioselective Mono‐ and Bis‐Sulfenylation of Active Methylene Compounds
Author(s) -
Devi Namita,
Rahaman Rajjakfur,
Sarma Kuladip,
Barman Pranjit
Publication year - 2016
Publication title -
european journal of organic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.825
H-Index - 155
eISSN - 1099-0690
pISSN - 1434-193X
DOI - 10.1002/ejoc.201501148
Subject(s) - chemistry , methylene , regioselectivity , catalysis , organic chemistry , iodine , solvent , combinatorial chemistry
Selective mono‐ and bis‐sulfenylation of active methylene groups with a variety of disulfides at an ambient temperature is reported. Sulfenylation is promoted by iodine as a catalyst and sulfenyl iodides as intermediates, under metal‐free conditions. The method is greener in terms of solvent selection and the use of less hazardous DMSO as an oxidant. The procedure is highly efficient with readily available starting materials, giving good to excellent yields.