Iodine‐Catalyzed Synthesis of Highly Functionalized 1 H ‐Indene Derivatives from Michael Adducts of  o ‐Alkynylarene Chalcones with Diethyl Malonate | Zendy

Akbar Sikkandarkani | Zendy; Srinivasan Kannupal | Zendy

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Iodine‐Catalyzed Synthesis of Highly Functionalized 1 H ‐Indene Derivatives from Michael Adducts of o ‐Alkynylarene Chalcones with Diethyl Malonate

Author(s) -

Akbar Sikkandarkani,

Srinivasan Kannupal

Publication year - 2015

Publication title -

european journal of organic chemistry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.825

H-Index - 155

eISSN - 1099-0690

pISSN - 1434-193X

DOI - 10.1002/ejoc.201501141

Subject(s) - chemistry , diethyl malonate , michael reaction , indene , adduct , malonate , isomerization , yield (engineering) , iodine , catalysis , organic chemistry , medicinal chemistry , materials science , metallurgy

Upon treatment with a substoichiometric amount of iodine in ethanol under reflux conditions, the Michael adducts of o ‐alkynylarene chalcones with diethyl malonate underwent 5‐ exo‐dig Conia‐ene cyclization followed by isomerization to yield highly functionalized 1 H ‐indene derivatives in good yields.

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