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An Enantiopure 5,5′‐Bitetracene
Author(s) -
Toyota Shinji,
Miyaji Ryutaro,
Yamamoto Yuta,
Inoue Masataka,
Wakamatsu Kan,
Iwanaga Tetsuo
Publication year - 2015
Publication title -
european journal of organic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.825
H-Index - 155
eISSN - 1099-0690
pISSN - 1434-193X
DOI - 10.1002/ejoc.201501135
Subject(s) - enantiopure drug , chemistry , enantiomer , derivative (finance) , absolute configuration , axial symmetry , chiral column chromatography , stereochemistry , computational chemistry , chirality (physics) , combinatorial chemistry , organic chemistry , enantioselective synthesis , chiral symmetry , catalysis , nambu–jona lasinio model , physics , structural engineering , quantum mechanics , quark , financial economics , engineering , economics
Two 5,5′‐bitetracene derivatives were synthesized from tetracenone in three steps as novel axially chiral biaryls. The enantiomers of 12,12′‐bis(phenylethynyl) derivative were successfully resolved by chiral HPLC. Their absolute stereochemistry was determined by theoretical calculations of the CD spectra using the time‐dependent (TD) DFT method.