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New Life for Diazoacetonitrile (N 2 CHCN): in situ Generation and Practical Synthesis of CN‐Pyrazoles
Author(s) -
Mykhailiuk Pavel K.
Publication year - 2015
Publication title -
european journal of organic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.825
H-Index - 155
eISSN - 1099-0690
pISSN - 1434-193X
DOI - 10.1002/ejoc.201501027
Subject(s) - chemistry , in situ , reagent , ethyl diazoacetate , explosive material , safer , combinatorial chemistry , organic chemistry , catalysis , cyclopropanation , computer science , computer security
Explosive diazoacetonitrile (N 2 CHCN) was generated in situ and used in the practical synthesis of agrochemistry‐related CN‐pyrazoles. In situ generated N 2 CHCN is much safer than the individual reagent. The developed method is, therefore, expected to make this reagent as useful in chemistry as ethyl diazoacetate (N 2 CHCO 2 Et).
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