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Hydrogenation of Aliphatic and Aromatic Nitriles Using a Defined Ruthenium PNP Pincer Catalyst
Author(s) -
Neumann Jacob,
Bornschein Christoph,
Jiao Haijun,
Junge Kathrin,
Beller Matthias
Publication year - 2015
Publication title -
european journal of organic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.825
H-Index - 155
eISSN - 1099-0690
pISSN - 1434-193X
DOI - 10.1002/ejoc.201501007
Subject(s) - chemistry , ruthenium , pincer movement , catalysis , nitrile , organic chemistry , noyori asymmetric hydrogenation , primary (astronomy) , combinatorial chemistry , medicinal chemistry , physics , astronomy
Selective catalytic reductions of nitriles are presented using the commercially available Ru‐Macho‐BH complex. A variety of aliphatic, aromatic and (hetero)cyclic nitriles including industrially important adipodinitrile are hydrogenated to the corresponding primary amines. Modelling suggests the reaction follows an outer sphere hydrogenation mechanism.