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Preparation of 6‐Difluoromethylphosphonated Phenanthridines by Visible‐Light‐Driven Radical Cyclization of 2‐Isocyanobiphenyls
Author(s) -
Wang Shuang,
Jia WenLiang,
Wang Lin,
Liu Qiang
Publication year - 2015
Publication title -
european journal of organic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.825
H-Index - 155
eISSN - 1099-0690
pISSN - 1434-193X
DOI - 10.1002/ejoc.201500988
Subject(s) - chemistry , photocatalysis , visible spectrum , photochemistry , radical cyclization , radical , molecule , organic chemistry , catalysis , physics , optoelectronics
A protocol to obtain a variety of 6‐difluoromethylenephosphonated phenanthridines through a radical cyclization process was explored. These reactions, performed with the use of diethyl bromodifluoromethylphosphonate as a radical resource and 2‐isocyanobiphenyls as radical acceptors, were smoothly triggered by visible‐light photocatalysis. Electron‐withdrawing and electron‐donating groups were well tolerated, and the target molecules were obtained in excellent to moderate yields.