Premium
Oxidative Heck Reaction of Fluorinated Olefins with Arylboronic Acids by Palladium Catalysis
Author(s) -
Li Yang,
Tu DongHuai,
Gu YuJie,
Wang Bo,
Wang YaoYu,
Liu ZhaoTie,
Liu ZhongWen,
Lu Jian
Publication year - 2015
Publication title -
european journal of organic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.825
H-Index - 155
eISSN - 1099-0690
pISSN - 1434-193X
DOI - 10.1002/ejoc.201500597
Subject(s) - chemistry , palladium , stereoselectivity , catalysis , heck reaction , oxidative phosphorylation , trifluoromethyl , oxidative addition , organic chemistry , combinatorial chemistry , medicinal chemistry , biochemistry , alkyl
The palladium‐catalyzed oxidative Heck reaction of 2,3,3,3‐tetrafluoroprop‐1‐ene with various arylboronic acids was explored for the first time. This method provides a direct route to access ( Z )‐β‐fluoro‐β‐(trifluoromethyl)styrenes with high stereoselectivity.
Accelerating Research
Robert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom
Address
John Eccles HouseRobert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom