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Oxidative Heck Reaction of Fluorinated Olefins with Arylboronic Acids by Palladium Catalysis
Author(s) -
Li Yang,
Tu DongHuai,
Gu YuJie,
Wang Bo,
Wang YaoYu,
Liu ZhaoTie,
Liu ZhongWen,
Lu Jian
Publication year - 2015
Publication title -
european journal of organic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.825
H-Index - 155
eISSN - 1099-0690
pISSN - 1434-193X
DOI - 10.1002/ejoc.201500597
Subject(s) - chemistry , palladium , stereoselectivity , catalysis , heck reaction , oxidative phosphorylation , trifluoromethyl , oxidative addition , organic chemistry , combinatorial chemistry , medicinal chemistry , biochemistry , alkyl
Abstract The palladium‐catalyzed oxidative Heck reaction of 2,3,3,3‐tetrafluoroprop‐1‐ene with various arylboronic acids was explored for the first time. This method provides a direct route to access ( Z )‐β‐fluoro‐β‐(trifluoromethyl)styrenes with high stereoselectivity.