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Fused Selenazolinium Salt Derivatives with a Se–N + Bond: Preparation and Properties
Author(s) -
Arsenyan Pavel,
Vasiljeva Jelena,
Belyakov Sergey,
Liepinsh Edvards,
Petrova Marina
Publication year - 2015
Publication title -
european journal of organic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.825
H-Index - 155
eISSN - 1099-0690
pISSN - 1434-193X
DOI - 10.1002/ejoc.201500582
Subject(s) - chemistry , oxidizing agent , salt (chemistry) , sulfur , organic chemistry , combinatorial chemistry , polymer chemistry
Convenient methods for the preparation of stable, fused selenazolinium salt systems with a Se–N + bond have been developed. The mechanism for the formation of the selenazole cycle was investigated in detail by conducting multinuclear NMR experiments. The ability of these compounds to form stable inner salts was demonstrated. We have shown the glutathione peroxidase (GPx) like properties of selenazolopyridinium salts by oxidizing sulfur‐containing natural amino acids, as well as aromatic and heteroaromatic aldehydes. The molecular structures of most of the compounds were confirmed by X‐ray diffraction studies.