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Conformational Switching in Heterochiral α,β 2,3 ‐Hybrid Peptides in Response to Solvent Polarity
Author(s) -
Balamurugan Dhayalan,
Muraleedharan Kannoth M.
Publication year - 2015
Publication title -
european journal of organic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.825
H-Index - 155
eISSN - 1099-0690
pISSN - 1434-193X
DOI - 10.1002/ejoc.201500534
Subject(s) - chemistry , solvation , polarity (international relations) , solvent polarity , peptide , stereochemistry , solvent , solvent effects , computational chemistry , crystallography , organic chemistry , biochemistry , cell
The ability of α,β 2,3 ‐hybrid peptides with a heterochiral backbone to exist in a helical, extended, or partially folded state depending on the solvation conditions employed was investigated. The preference was found to be directly dictated by C α –C β torsions in the β‐residues.
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