Premium
A Flexible Route to Indole Scaffolds – Formal Synthesis of (±)‐Mersicarpine
Author(s) -
Pfaffenbach Magnus,
Gaich Tanja
Publication year - 2015
Publication title -
european journal of organic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.825
H-Index - 155
eISSN - 1099-0690
pISSN - 1434-193X
DOI - 10.1002/ejoc.201500309
Subject(s) - chemistry , formal synthesis , flexibility (engineering) , simple (philosophy) , indole test , combinatorial chemistry , indole alkaloid , stereochemistry , philosophy , statistics , mathematics , epistemology
The formal synthesis of racemic mersicarpine was accomplished in an operationally simple, reliable, and efficient manner in eight isolated steps. The use of a common intermediate increases the degree of synthetic flexibility and allows the construction of two completely different polycyclic alkaloid skeletons.