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The Nugent Reagent: A Formidable Tool in Contemporary Radical and Organometallic Chemistry
Author(s) -
Rosales Antonio,
RodríguezGarcía Ignacio,
MuñozBascón Juan,
RoldanMolina Esther,
Padial Natalia M.,
Morales Laura Pozo,
GarcíaOcaña Marta,
Oltra J. Enrique
Publication year - 2015
Publication title -
european journal of organic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.825
H-Index - 155
eISSN - 1099-0690
pISSN - 1434-193X
DOI - 10.1002/ejoc.201500292
Subject(s) - chemistry , reagent , organic chemistry , environmentally friendly , organic synthesis , combinatorial chemistry , catalysis , ecology , biology
The vast range of reactions mediated by titanocene monochloride (Cp 2 TiCl, the Nugent reagent) in organic synthetic chemistry is reviewed. The power of the Nugent reagent in organic chemistry is demonstrated by its ability to promote and/or catalyse several efficient transformations under mild reaction conditions in the presence of several functional groups, in an environmentally friendly manner and with use of simple experimental procedures.