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Palladium‐Catalyzed Regioselective Cross‐Dehydrogenative Coupling of Benzofurans with Uracils at Room Temperature
Author(s) -
Kianmehr Ebrahim,
Torabi Mehrdad,
Rezazadeh Khalkhali Mehran,
Faghih Nasser,
Khan Khalid Mohammed
Publication year - 2015
Publication title -
european journal of organic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.825
H-Index - 155
eISSN - 1099-0690
pISSN - 1434-193X
DOI - 10.1002/ejoc.201500042
Subject(s) - chemistry , regioselectivity , benzofuran , palladium , uracil , catalysis , combinatorial chemistry , medicinal chemistry , organic chemistry , biochemistry , dna
The Pd‐catalyzed cross‐dehydrogenative coupling (CDC) between two heteroarenes was developed. A variety of benzofuran and uracil derivatives were constructed through C–C bond formation by using CDC reactions. The substrates did not require prefunctionalization, and the products were obtained in good yields with good regioselectivities at room temperature.