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Synthesis of a Photostable Energy‐Transfer Pair for “DNA Traffic Lights” (Eur. J. Org. Chem. 34/2014)
Author(s) -
Bohländer Peggy R.,
Wagenknecht HansAchim
Publication year - 2014
Publication title -
european journal of organic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.825
H-Index - 155
eISSN - 1099-0690
pISSN - 1434-193X
DOI - 10.1002/ejoc.201490096
Subject(s) - chemistry , oligonucleotide , dna , energy transfer , förster resonance energy transfer , covalent bond , fluorescence , photochemistry , chemical physics , biochemistry , organic chemistry , optics , physics
The cover picture shows the green‐to‐red fluorescence color change upon annealing of a single‐stranded oligonucleotide to double‐stranded DNA. The color change is based on efficient energy transfer between two dyes that are covalently attached to a 2′‐position in each oligonucleotide. Both dyes are highly photostable, which is a key requirement for using “DNA traffic lights” in long‐term cellular and molecular imaging applications. Details are discussed in the Short Communication by P. R. Bohländer and H.‐A. Wagenknecht on. 7547 ff .