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A Planar‐Chiral Phosphino(alkenyl)ferrocene for Suzuki–Miyaura C–C Coupling Reactions (Eur. J. Org. Chem. 30/2014)
Author(s) -
Schaarschmidt Dieter,
Grumbt Martin,
Hildebrandt Alexander,
Lang Heinrich
Publication year - 2014
Publication title -
european journal of organic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.825
H-Index - 155
eISSN - 1099-0690
pISSN - 1434-193X
DOI - 10.1002/ejoc.201490084
Subject(s) - ferrocene , chemistry , steric effects , representation (politics) , planar chirality , coupling (piping) , planar , computational chemistry , stereochemistry , enantioselective synthesis , organic chemistry , catalysis , electrochemistry , law , mechanical engineering , computer graphics (images) , electrode , engineering , politics , political science , computer science
The cover picture shows the graphical representation of a planar‐chiral phosphino(alkenyl)ferrocene in a fictional pass in the Erzgebirge (Ore Mountains) at the junction of two paths. The article by H. Lang et al. on p. 6676 ff describes the use of this compound for the atropselective synthesis of sterically congested biaryls by a Suzuki–Miyaura coupling. One of these biaryls is depicted in the back of the cartoon. This research is motivated by the fact that the synthesis of sterically congested biaryls and atropselective biaryl couplings are almost exclusively considered as individual topics. In this respect, the ferrocene unit is excellently suited to combine these two fields exerting the intrinsic chirality of 1,2‐heterodisubstituted ferrocenes. Investigations demonstrating proof of principle are presented in this article. Reference to Chemnitz, the hometown of the authors, is made by the colourful chimney, the newest landmark in the region, which is the highest building in Saxony.