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Formal Intermolecular Hydroamination of Unbiased Olefins for Primary Amine Formation
Author(s) -
Yang Yongsheng,
Wong Nurul Imma,
Teo Peili
Publication year - 2015
Publication title -
european journal of organic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.825
H-Index - 155
eISSN - 1099-0690
pISSN - 1434-193X
DOI - 10.1002/ejoc.201403654
Subject(s) - hydroamination , chemistry , intermolecular force , catalysis , amine gas treating , primary (astronomy) , tandem , organic chemistry , ammonia , combinatorial chemistry , polymer chemistry , molecule , astronomy , composite material , physics , materials science
Abstract A Pd/Ir dual metal tandem catalyst system was found to be active in catalyzing the one‐pot, two‐step formal hydroamination of unbiased olefins such as 1‐dodecene with an ammonia source to give branched primary amines in high yields of >85 % by using only 1 mol‐% of the Ir catalyst. This is the first report of the formal one‐pot intermolecular hydroamination of olefins to obtain primary amines.