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Oxime‐Mediated Oxychlorination and Oxybromination of Unactivated Olefins
Author(s) -
Dong KuiYong,
Qin HaiTao,
Liu Feng,
Zhu Chen
Publication year - 2015
Publication title -
european journal of organic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.825
H-Index - 155
eISSN - 1099-0690
pISSN - 1434-193X
DOI - 10.1002/ejoc.201403538
Subject(s) - chemistry , oxime , palladium , catalysis , organic chemistry , raw material , combinatorial chemistry
An oxime‐mediated oxychlorination and oxybromination of unactivated olefins relying on palladium catalysis has been developed. A wide range of chlorinated and brominated isoxazolines has been synthesized in moderate to good yields. To demonstrate the value of the method, the brominated isoxazoline has been further converted to other useful synthetic feedstock.