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2‐Furanylboronic Acid as an Effective Catalyst for the Direct Amidation of Carboxylic Acids at Room Temperature
Author(s) -
Tam Eric Kwok Wai,
Liu Lionel Yiqian,
Chen Anqi
Publication year - 2015
Publication title -
european journal of organic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.825
H-Index - 155
eISSN - 1099-0690
pISSN - 1434-193X
DOI - 10.1002/ejoc.201403468
Subject(s) - chemistry , carboxylic acid , catalysis , amide , primary (astronomy) , organic chemistry , combinatorial chemistry , physics , astronomy
2‐Furanylboronic acid has been identified as an inexpensive and effective catalyst for the dehydrative amide formation of carboxylic acids and amines. This transformation can be efficiently carried out at room temperature and is applicable to a wide range of carboxylic acids with primary and secondary amines to afford amides in good to excellent yields.