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Palladium‐Catalyzed α‐Selective Alkenylation of Imidazo[1,2‐ a ]pyridines through Aerobic Cross‐Dehydrogenative Coupling Reaction
Author(s) -
Ghosh Monoranjan,
Naskar Aswini,
Mitra Shubhanjan,
Hajra Alakananda
Publication year - 2015
Publication title -
european journal of organic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.825
H-Index - 155
eISSN - 1099-0690
pISSN - 1434-193X
DOI - 10.1002/ejoc.201403372
Subject(s) - chemistry , palladium , regioselectivity , catalysis , coupling reaction , molecular oxygen , coupling (piping) , combinatorial chemistry , reaction conditions , oxygen , organic chemistry , mechanical engineering , engineering
The palladium‐catalyzed highly regioselective vinylation of imidazopyridines through a cross‐dehydrogenative coupling reaction was developed. The reaction proceeds with the aid of molecular oxygen as the sole oxidant. A series of branched α‐vinylated products were obtained with high efficiency.