Premium
Transition‐Metal‐Free Oxidative Iodination of 1,3,4‐Oxadiazoles
Author(s) -
Dannenberg Carl Albrecht,
Bizet Vincent,
Zou LiangHua,
Bolm Carsten
Publication year - 2015
Publication title -
european journal of organic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.825
H-Index - 155
eISSN - 1099-0690
pISSN - 1434-193X
DOI - 10.1002/ejoc.201403352
Subject(s) - chemistry , selectfluor , halogenation , halide , transition metal , sodium iodide , oxidative phosphorylation , iodide , iodine , combinatorial chemistry , organic chemistry , inorganic chemistry , catalysis , biochemistry
Abstract Transition‐metal‐free oxidative iodination of 2‐substituted 1,3,4‐oxadiazoles was achieved by using sodium iodide as the halide source and Selectfluor as the oxidant. Variously substituted products were obtained in moderate to good yields under operationally straightforward conditions. Compared to existing methods for analogous conversions, the newly developed protocol appears synthetically attractive.