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Light‐Mediated Deoxygenation of Alcohols with a Dimeric Gold Catalyst
Author(s) -
McCallum Terry,
Slavko Ekaterina,
Morin Mathieu,
Barriault Louis
Publication year - 2015
Publication title -
european journal of organic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.825
H-Index - 155
eISSN - 1099-0690
pISSN - 1434-193X
DOI - 10.1002/ejoc.201403351
Subject(s) - deoxygenation , chemistry , catalysis , halogenation , combinatorial chemistry , photoredox catalysis , organic chemistry , tertiary alcohols , photochemistry , photocatalysis
A new protocol for the reductive deoxygenation of primary alcohols was explored. This photomediated method combines a novel approach to bromination of alcohols merged with the powerful reducing capability of [Au 2 (dppm) 2 ]Cl 2 [dppm = 1,1‐bis(diphenylphosphino)methane] as a photoredox catalyst. The highly efficient methods discussed are marked by the use of UVA light‐emitting diodes, which have significantly reduced reaction times and lowered setup cost.