Premium
Synthesis of ( E )‐1,4‐Enediones from α‐Halo Ketones Through a Sodium Sulfinate Mediated Reaction
Author(s) -
Li SuYi,
Wang XiaoBing,
Jiang Neng,
Kong LingYi
Publication year - 2014
Publication title -
european journal of organic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.825
H-Index - 155
eISSN - 1099-0690
pISSN - 1434-193X
DOI - 10.1002/ejoc.201403236
Subject(s) - chemistry , halo , sodium , selectivity , reaction conditions , combinatorial chemistry , organic chemistry , catalysis , physics , quantum mechanics , galaxy
We developed a mild and practical protocol for the synthesis of 1,4‐enedione from α‐halo ketones through a sodium sulfinate mediated reaction. This reaction enables the construction of symmetric and unsymmetric 1,4‐enedione with complete E selectivity. Sodium 4‐toluenesulfinate plays an important role in this reaction.
Accelerating Research
Robert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom
Address
John Eccles HouseRobert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom