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Superstable Palladium(0) Complex as an Air‐ and Thermostable Catalyst for Suzuki Coupling Reactions
Author(s) -
Jakab Alexandra,
Dalicsek Zoltán,
Holczbauer Tamás,
Hamza Andrea,
Pápai Imre,
Finta Zoltán,
Timári Géza,
Soós Tibor
Publication year - 2015
Publication title -
european journal of organic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.825
H-Index - 155
eISSN - 1099-0690
pISSN - 1434-193X
DOI - 10.1002/ejoc.201403214
Subject(s) - chemistry , palladium , phosphine , catalysis , ligand (biochemistry) , suzuki reaction , non covalent interactions , combinatorial chemistry , computational chemistry , coupling reaction , coupling (piping) , organic chemistry , molecule , biochemistry , hydrogen bond , receptor , mechanical engineering , engineering
An unprecedentedly thermo‐ and air‐stable Pd 0 complex from readily available electron‐poor trifluoromethylated phosphine was serendipitously discovered. As detailed and comparative DFT calculations indicate, the stability of the complex is associated with unusually strong ligand–ligand noncovalent interactions. The unique stability and the presence of hydrophobic structural elements of the complex offer several practical advantages, which were exploited in catalytic Suzuki–Miyaura coupling reactions.