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Synthesis of Chiral Functionalised Cyclobutylpyrrolidines and Cyclobutylamino Alcohols from (–)‐( S )‐Verbenone – Applications in the Stabilisation of Ruthenium Nanocatalysts
Author(s) -
Aguilera Jordi,
Favier Isabelle,
Sans Marta,
Mor Àlex,
ÁlvarezLarena Ángel,
Illa Ona,
Gómez Montserrat,
Ortuño Rosa M.
Publication year - 2015
Publication title -
european journal of organic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.825
H-Index - 155
eISSN - 1099-0690
pISSN - 1434-193X
DOI - 10.1002/ejoc.201403176
Subject(s) - chemistry , ruthenium , aniline , organic chemistry , catalysis , nitrobenzene , enantioselective synthesis , nanomaterial based catalyst , stereoselectivity , cyclohexane , combinatorial chemistry , noyori asymmetric hydrogenation
Stereoselective and efficient synthetic routes to pyrrolidines and amino alcohols anchored to chiral polysubstituted cyclobutane moieties have been developed from (–)‐( S )‐verbenone. These original frameworks, in particular the diamines and amino alcohols, are appropriate stabilisers of metallic nanoparticles, especially for the synthesis of ruthenium nanomaterials, which found catalytic applications in the hydrogenation of arenes and nitrobenzene derivatives to afford selectively the corresponding cyclohexane or aniline derivatives.