Synthesis of Vinyl‐ and Aryl–Acyl Sulfonimidamides Through Pd‐Catalyzed Carbonylation Using Mo(CO) 6 as ex situ CO Source

We report the synthesis of N ‐(α,β‐unsaturated acyl)‐substituted sulfonimidamides through a Pd‐catalyzed carbonylation protocol, employing sulfonimidamides as nucleophiles using CO gas released ex situ, and vinyl/aryl halides and triflates as reagents. The reaction is general and offers a unique class of products in moderate to good yields for a wide range of substrates and electrophiles; for example, aliphatic, aromatic (electron‐donating and ‐withdrawing groups), heteroaryl, vinyl halides, and triflates. We also expand our initial report on N ‐aryl–acyl‐substituted sulfonimidamide synthesis by employing aryltriflates as electrophiles. Furthermore, we report a surprisingly facile thermolytic Boc deprotection of N ‐(α,β‐unsaturated acyl) sulfonimidamides.