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Carbon–Phosphorus Bond Formation by Enantioselective Palladium‐Catalyzed Allylation of Diphenylphosphine Oxide
Author(s) -
Zhang Liang,
Liu Wei,
Zhao Xiaoming
Publication year - 2014
Publication title -
european journal of organic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.825
H-Index - 155
eISSN - 1099-0690
pISSN - 1434-193X
DOI - 10.1002/ejoc.201403024
Subject(s) - chemistry , diphenylphosphine oxide , allylic rearrangement , enantioselective synthesis , diphenylphosphine , phosphonate , palladium , catalysis , medicinal chemistry , organic chemistry , phosphorus , phosphine
The enantioselective Pd‐catalyzed allylation of diaryl‐substituted allylic carbonates and diphenylphosphine oxide was investigated. This method gave allylic diphenylphosphine oxides in yields up to 95 % with 97 % ee . Pd‐catalyzed allylation of ( E )‐methyl allyl carbonates with diisopropyl phosphonate was also examined.