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Isohexides as Versatile Scaffolds for Asymmetric Catalysis
Author(s) -
Kadraoui Mohammed,
Maunoury Thibault,
Derriche Zoubir,
Guillarme Stéphane,
Saluzzo Christine
Publication year - 2015
Publication title -
european journal of organic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.825
H-Index - 155
eISSN - 1099-0690
pISSN - 1434-193X
DOI - 10.1002/ejoc.201402851
Subject(s) - chemistry , enantioselective synthesis , catalysis , combinatorial chemistry , ring (chemistry) , organocatalysis , stereochemistry , organic chemistry
This review presents an overview of the use of dianhydrohexitol derivatives as asymmetric ligands in organometallic catalysis or as asymmetric organocatalysts. For that purpose, we highlight two series of derivatives, the first preserving the original bis‐fused THF backbones, and the second originating from single THF ring‐opening reactions. These derivatives have been involved in different asymmetric reactions for the formation of C–H, C–C, C–N, or C–S bonds.