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A General, Regiospecific Synthetic Route to Perfluoroalkylated Arenes via Arenediazonium Salts with R F Cu(CH 3 CN) Complexes
Author(s) -
Jiang DongFang,
Liu Chao,
Guo Yong,
Xiao JiChang,
Chen QingYun
Publication year - 2014
Publication title -
european journal of organic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.825
H-Index - 155
eISSN - 1099-0690
pISSN - 1434-193X
DOI - 10.1002/ejoc.201402820
Subject(s) - chemistry , ether , trapping , medicinal chemistry , organic chemistry , polymer chemistry , combinatorial chemistry , biology , ecology
A mild method of converting arylamines into perfluoroalkylated arenes is described. Relatively stable R F Cu(CH 3 CN) complexes are used as perfluoroalkylating agents, which react smoothly with arenediazonium salts to produce various perfluoroalkylarenes in good yields. Based on the results of clock trapping experiments with diallyl ether, a radical process might be involved in the reaction.