Indium‐Catalyzed Hydroamination/Hydrosilylation of Terminal Alkynes and Aromatic Amines through a One‐Pot, Two‐Step Protocol | Zendy

Sakai Norio | Zendy; Takahashi Nobuaki | Zendy; Ogiwara Yohei | Zendy

Premium

Indium‐Catalyzed Hydroamination/Hydrosilylation of Terminal Alkynes and Aromatic Amines through a One‐Pot, Two‐Step Protocol

Author(s) -

Sakai Norio,

Takahashi Nobuaki,

Ogiwara Yohei

Publication year - 2014

Publication title -

european journal of organic chemistry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.825

H-Index - 155

eISSN - 1099-0690

pISSN - 1434-193X

DOI - 10.1002/ejoc.201402544

Subject(s) - hydrosilylation , chemistry , hydroamination , markovnikov's rule , catalysis , organic chemistry , imine , tribromide , substrate (aquarium) , indium , combinatorial chemistry , polymer chemistry , regioselectivity , oceanography , geology

We demonstrated that indium tribromide effectively functioned as a single catalyst for two successive steps in a one‐pot procedure. First, the hydroamination of alkynes with anilines took place to give the Markovnikov product. Then, hydrosilylation of the imine intermediates by treatment with a hydrosilane substrate afforded the corresponding secondary amines.

This content is not available in your region!

Continue researching here.

Having issues? You can contact us here

Accelerating Research