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Iodine‐Mediated Oxidation of Ynamides: A Facile Access to N ‐Monosubstituted α‐Ketoamides and α‐Ketoimides
Author(s) -
Huang Hai,
He Guangke,
Zhu Xiaolin,
Jin Xiaodong,
Qiu Shineng,
Zhu Hongjun
Publication year - 2014
Publication title -
european journal of organic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.825
H-Index - 155
eISSN - 1099-0690
pISSN - 1434-193X
DOI - 10.1002/ejoc.201402538
Subject(s) - chemistry , iodine , catalysis , functional group , oxidative phosphorylation , reaction conditions , combinatorial chemistry , metal , redox , organic chemistry , medicinal chemistry , biochemistry , polymer
An efficient iodine‐mediated oxidation reaction for ynamides has been developed to produce N ‐monosubstituted α‐ketoamides and α‐ketoimides. This oxidative method, which exhibits good functional group tolerance, was performed under mild conditions without a metal catalyst.
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