Premium
Palladium‐Catalyzed Decarboxylative C–H Bond Arylation of Furans
Author(s) -
Pei Kai,
Jie Xiaoming,
Zhao Huaiqing,
Su Weiping
Publication year - 2014
Publication title -
european journal of organic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.825
H-Index - 155
eISSN - 1099-0690
pISSN - 1434-193X
DOI - 10.1002/ejoc.201402278
Subject(s) - chemistry , decarboxylation , palladium , catalysis , substrate (aquarium) , organic chemistry , surface modification , combinatorial chemistry , medicinal chemistry , geology , oceanography
A Pd/PCy 3 /Ag 2 CO 3 (Cy = cyclohexyl) catalytic system was found to promote decarboxylative arylation through the combination of decarboxylation and C–H bond functionalization. This protocol features a good substrate scope of aromatic carboxylic acids as well as a broad range of functional groups and provides the products in high yields.
Accelerating Research
Robert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom
Address
John Eccles HouseRobert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom