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Palladium‐Catalyzed Decarboxylative C–H Bond Arylation of Furans
Author(s) -
Pei Kai,
Jie Xiaoming,
Zhao Huaiqing,
Su Weiping
Publication year - 2014
Publication title -
european journal of organic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.825
H-Index - 155
eISSN - 1099-0690
pISSN - 1434-193X
DOI - 10.1002/ejoc.201402278
Subject(s) - chemistry , decarboxylation , palladium , catalysis , substrate (aquarium) , organic chemistry , surface modification , combinatorial chemistry , medicinal chemistry , geology , oceanography
A Pd/PCy 3 /Ag 2 CO 3 (Cy = cyclohexyl) catalytic system was found to promote decarboxylative arylation through the combination of decarboxylation and C–H bond functionalization. This protocol features a good substrate scope of aromatic carboxylic acids as well as a broad range of functional groups and provides the products in high yields.