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Efficient C–N and C–S Bond Formation Using the Highly Active [Ni(allyl)Cl(IPr* OMe )] Precatalyst
Author(s) -
Martin Anthony R.,
Nelson David J.,
Meiries Sébastien,
Slawin Alexandra M. Z.,
Nolan Steven P.
Publication year - 2014
Publication title -
european journal of organic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.825
H-Index - 155
eISSN - 1099-0690
pISSN - 1434-193X
DOI - 10.1002/ejoc.201402022
Subject(s) - chemistry , carbene , medicinal chemistry , imidazole , catalysis , halide , amination , aryl , nickel , aryl halide , palladium , stereochemistry , organic chemistry , alkyl
Two new [Ni(allyl)Cl(NHC)] complexes with the bulky yet flexible N‐heterocyclic carbene (NHC) ligands IPr* { N , N′ ‐bis[2,6‐bis(diphenylmethyl)‐4‐methylphenyl]imidazole‐2‐ylidene} and IPr* OMe { N , N′ ‐bis[2,6‐bis(diphenylmethyl)‐4‐methoxyphenyl]imidazol‐2‐ylidene} are reported. These complexes were employed in the amination and sulfination of aryl halide species and were shown to perform well in these reactions, which typically required less than half as much catalyst as previous state‐of‐the‐art nickel complexes.