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Palladium‐Catalyzed C–H Acylation of Arenes Using Thioethers as Directing Groups
Author(s) -
Xu Bo,
Liu Wei,
Kuang Chunxiang
Publication year - 2014
Publication title -
european journal of organic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.825
H-Index - 155
eISSN - 1099-0690
pISSN - 1434-193X
DOI - 10.1002/ejoc.201400096
Subject(s) - acylation , chemistry , palladium , regioselectivity , catalysis , organic chemistry , combinatorial chemistry , medicinal chemistry
A highly efficient protocol for regioselective synthesis of diaryl ketones by palladium‐catalyzed direct acylation of arenes using thioethers as directing groups is reported. The possible pathway of direct acylation between thioethers and α‐oxocarboxylic acids is discussed.