Access to 3‐Arylindoles through a Tandem One‐Pot Protocol Involving Dearomatization, a Regioselective Michael Addition Reaction, and Rearomatization | Zendy

Chittimalla Santhosh Kumar | Zendy; Bandi Chennakesavulu | Zendy; Putturu Sireesha | Zendy; Kuppusamy Rajesh | Zendy; Boellaard Kevin Christopher | Zendy; Tan David Chu Aan | Zendy; Lum Demi Ming Jie | Zendy

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Access to 3‐Arylindoles through a Tandem One‐Pot Protocol Involving Dearomatization, a Regioselective Michael Addition Reaction, and Rearomatization

Author(s) -

Chittimalla Santhosh Kumar,

Bandi Chennakesavulu,

Putturu Sireesha,

Kuppusamy Rajesh,

Boellaard Kevin Christopher,

Tan David Chu Aan,

Lum Demi Ming Jie

Publication year - 2014

Publication title -

european journal of organic chemistry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.825

H-Index - 155

eISSN - 1099-0690

pISSN - 1434-193X

DOI - 10.1002/ejoc.201400079

Subject(s) - regioselectivity , chemistry , tandem , michael reaction , combinatorial chemistry , organic chemistry , catalysis , materials science , composite material

A facile, general and rapid protocol for the introduction of oxygenated aryls at the 3‐position of indoles is described. This approach consists of a tandem dearomatization, a regioselective Michael addition reaction, and rearomatization in a one‐pot three‐step sequence to obtain 3‐arylindoles in good yields.

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