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Gold(I)‐Catalyzed Hydration of Alkynylphosphonates: Efficient Access to β‐Ketophosphonates
Author(s) -
Xie Longyong,
Yuan Rui,
Wang Ruijia,
Peng Zhihong,
Xiang Jiannan,
He Weimin
Publication year - 2014
Publication title -
european journal of organic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.825
H-Index - 155
eISSN - 1099-0690
pISSN - 1434-193X
DOI - 10.1002/ejoc.201400066
Subject(s) - chemistry , regioselectivity , catalysis , transformation (genetics) , functional group , reaction conditions , combinatorial chemistry , organic chemistry , biochemistry , polymer , gene
A general, efficient, and highly regioselective protocol with the use of a gold(I) complex catalytic system for the transformation of alkynylphosphonates into the corresponding β‐ketophosphonates has been successfully developed. This method produces a variety of β‐ketophosphonates with the advantages of mild reaction conditions, high functional‐group tolerance, and excellent yields.