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Selective Glycosylation with the Amino Sugar D ‐Forosamine for the Synthesis of Spinosyns and Its Analogues (Eur. J. Org. Chem. 32/2013)
Author(s) -
Tietze Lutz F.,
Dietz Simone,
Schützenmeister Nina,
Biller Simon,
Hierold Judith,
Scheffer Timo,
Baag Mohammad M.
Publication year - 2013
Publication title -
european journal of organic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.825
H-Index - 155
eISSN - 1099-0690
pISSN - 1434-193X
DOI - 10.1002/ejoc.201390091
Subject(s) - chemistry , glycosidic bond , glycosylation , sugar , amino acid , stereochemistry , biochemistry , enzyme
The cover picture shows an analogue of the spinosyns, which are important, commercially used, natural insecticides for a broad variety of crops, such as corn and potatoes, since they are completely nontoxic to mammals with only minor effects on nontarget insects and fishes. A crucial aspect in the synthesis of these compounds and of analogues is the introduction of a β‐glycosidic bond with the amino sugar D ‐forosamine, which is necessary for bioactivity. Details are discussed in the article by L. F. Tietze et al. on p. 7305 ff.