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Synthesis of Axially Chiral 1,1′‐Binaphthalenes by Palladium‐Catalysed Cross‐Coupling Reactions of Triorganoindium Reagents (Eur. J. Org. Chem. 13/2013)
Author(s) -
Mosquera Ángeles,
Pena Miguel A.,
Pérez Sestelo José,
Sarandeses Luis A.
Publication year - 2013
Publication title -
european journal of organic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.825
H-Index - 155
eISSN - 1099-0690
pISSN - 1434-193X
DOI - 10.1002/ejoc.201390033
Subject(s) - chemistry , palladium , reagent , enantioselective synthesis , indium , enantiomer , combinatorial chemistry , ligand (biochemistry) , catalysis , stereochemistry , organic chemistry , biochemistry , receptor
The cover picture shows a view of the Tower of Hercules in A Coruña (Spain), the oldest lighthouse in the world. The scheme illustrates the synthesis of chiral 1,1′‐binaphthalenes by palladium‐catalyzed cross‐coupling with triorganoindium reagents. Key features of the reaction are the transfer of the three groups attached to the indium atom and the high versatility of the indium reagents. Additionally, the enantioselective synthesis of binaphthyls can be performed, and the best enantiomeric excesses are obtained by using ( R , S )‐PPFA as chiral ligand. Details are discussed in the article by J. Pérez Sestelo, L. A. Sarandeses et al. on p. 2555 ff.